Fabrication: The Diederik Stapel case

One of the most discussed case of fabricated data comes from the Netherlands. Diederik Stapel was a professor of Social Psychology at Tilburg University and the University of Groningen. Some of his research was featured on news sites, such as his Science paper that found that people discriminate more in messy environments or another (unpublished) study that thinking about meat made people less social.

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Falsification: Haruko Obokata case

STAP treatment papers

Haruko Obokata was a researcher and laboratory head at the Japanese Riken Center for Developmental Biology. In 2014, she published 2 Nature papers (here and here) in which she described an acid treatment to turn somatic cells (mouse blood cells) into pluripotent stem cells, a method that she named “stimulus-triggered acquisition of pluripotency” or STAP.

Hours after publication, serious doubts about the validity of the paper were raised on Paul Knoepfler’s blog and PubPeer. Soon, people noticed similarities between photos in the Nature papers and those found in Obokata’s PhD thesis, in which these photos represented different experiments than those described in the Nature papers. In addition, no one was able to reproduce the STAP treatment, which just sounded too simple to be true.

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