Post-Publication Peer Review – Science Integrity Digest

Cassava Sciences: Of Posters and Spaghetti Plots

In a previous blog post, I took a look at Western blots in papers from the lab of Dr. Hoau-Yan Wang at City University of New York (CUNY), mostly related to Cassava Sciences (Nasdaq: $SAVA), its predecessor Pain Therapeutics INC, and its flagship Alzheimer’s Disease drug candidate Simufilam.

While those papers were mainly about the preclinical Simufilam data, here I will review a conference poster reporting on Phase 2 data obtained by Cassava Sciences.

Worst paper of 2020? 5G and Coronavirus induction

This paper made my jaw drop:

5G Technology and induction of coronavirus in skin cells – M Fioranelli et al. – J Biol Regul Homeost Agents 2020 Jul 16;34(4). doi: 10.23812/20-269-E-4 [archived – PDF]

The paper suggests that 5G waves (the latest cell phone technology) can spontaneously generate Coronaviruses in skin cells. Yet, there is nothing in this article that proves this extraordinary claim. It is absolute nonsense.

Combining two hot topics into one title, this article is surely asking for some attention. Attention it will get. Because it is one of the worst scientific papers I have seen this year.

Post-publication reviews on COVID-19 papers

We are in the midst of a viral pandemic with huge effects on human health, social interactions, and the economy. Suddenly, lots of people have opinions or claim to have solutions to solve the COVID-19 situation. Not surprisingly, the Coronavirus epidemic has led to an enormous input of scientific papers, editorials, letters, reviews, trials, and what have you not. Most of these have been written hastily, without the rigor and thoughtfulness and editing that are normally essential to scientific publishing. Some of these papers are great, many of them not so much. Social media is exploding with all kinds of post-publication reviews of heavily discussed scientific papers. This post is an attempt to collect critical reviews of some of these COVID-19 related scientific papers.

PubPeer – a website to comment on scientific papers

If you are interested in scientific integrity, you will probably know PubPeer, a website where you can leave anonymous or signed comments on scientific papers.

PubPeer was launched in late 2012 by neuroscientist Brendon Stell and brothers Richard and George Smith, with Boris Barbour and Gabor Brasnjo acting as advisers. At the start, the founders and advisers were anonymous, but they revealed their identity in 2015.

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